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dc.contributor.authorTashbayev, Behzod
dc.contributor.authorGaren, Torhild Oddveig
dc.contributor.authorPalm, Øyvind
dc.contributor.authorChen, Xiangjun
dc.contributor.authorHerlofson, Bente Brokstad
dc.contributor.authorYoung Vik, Alix Rosslyn
dc.contributor.authorHove, Lene Hystad
dc.contributor.authorRykke, Morten
dc.contributor.authorSingh, Preet Bano
dc.contributor.authorAqrawi, Lara Adnan
dc.contributor.authorUtheim, Øygunn Aass
dc.contributor.authorUtheim, Tor Paaske
dc.contributor.authorJensen, Janicke Cecilie Liaaen
dc.date.accessioned2020-05-18T06:14:16Z
dc.date.available2020-05-18T06:14:16Z
dc.date.created2020-03-07T20:58:58Z
dc.date.issued2020
dc.identifier.citationScientific Reports. 2020, 10 (2063).en_US
dc.identifier.issn2045-2322
dc.identifier.urihttps://hdl.handle.net/11250/2654673
dc.descriptionOpen Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, Sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder.en_US
dc.description.abstractUnderstanding the impact of the disease on quality of life is crucial in patient management. In this cross-sectional study, general and oral health-related quality of life questionnaires, and thorough examinations of oral and ocular dryness were performed in age- and sex-matched patients with primary Sjögren’s syndrome (pSS group), non-Sjögren’s syndrome sicca (non-SS group) and healthy controls. General and oral health-related quality of life were investigated with the 36-Item Short Form Health Survey and the 14-Item Oral Health Impact Profile questionnaires, respectively. Subjective symptoms of xerostomia and ocular dryness were recorded using the Summated Xerostomia Inventory and Ocular Surface Disease Index, respectively. Clinical examinations included evaluation of clinical oral dryness scores, candida counts, unstimulated and stimulated saliva secretory rates, tear osmolarity, tear film break-up time, Schirmer I test and ocular surface staining. Both patient groups had pronounced signs and symptoms of xerostomia and ocular dryness. Even though the non-SS patients had less severe clinical signs than the pSS patients, they demonstrated much poorer general and oral health-related quality of life. In conclusion, non-SS patients require more attention in order to improve their quality of life.en_US
dc.language.isoengen_US
dc.rightsNavngivelse 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titlePatients with non-Sjögren's sicca report poorer general and oral health-related quality of life than patients with Sjögren's syndrome: a cross-sectional studyen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© The Author(s) 2020en_US
dc.source.volume10en_US
dc.source.journalScientific Reportsen_US
dc.source.issue2063en_US
dc.identifier.doi10.1038/s41598-020-59078-0
dc.identifier.cristin1800324
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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