Browsing USN Open Archive by Author "Ræder, Sten"

Now showing items 1-10 of 10

    • Diagnostic Test Efficacy of Meibomian Gland Morphology and Function 

      Xiao, Jiaxin; Adil, Muhammed Yasin; Olafsson, Jonatan; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Lagali, Neil; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2019)
      Meibomian gland dysfunction (MGD) is the leading cause of dry eye and proposed treatments are based on disease severity. Our purpose was to establish reliable morphologic measurements of meibomian glands for evaluating MGD ...

    • Effects of explant size on epithelial outgrowth, thickness, stratification, ultrastructure and phenotype of cultured limbal epithelial cells 

      Utheim, Øygunn Aass; Pasovic, Lara; Ræder, Sten; Eidet, Jon Roger; Fostad, Ida; Sehic, Amer; Roald, Borghild; de la Paz, Maria Fideliz; Lyberg, Torstein; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2019)
      Purpose Transplantation of limbal stem cells is a promising therapy for limbal stem cell deficiency. Limbal cells can be harvested from either a healthy part of the patient’s eye or the eye of a donor. Small explants are ...

    • Functional and Morphological Evaluation of Meibomian Glands in the Assessment of Meibomian Gland Dysfunction Subtype and Severity 

      Xiao, Jiaxin; Adil, Muhammed Yasin; Chen, Xiangjun; Utheim, Øygunn A.; Ræder, Sten; Tønseth, Kim Alexander; Lagali, Neil S.; Dartt, Darlene A.; Utheim, Tor Paaske (Peer reviewed; Journal article, 2019)
      Purpose To classify subtypes of meibomian gland dysfunction (MGD) and evaluate the dependency of dry eye signs, symptoms, and parameters on MGD subtype. Design Cross-sectional study. Study Population: the right eyes ...

    • Meibomian gland dysfunction is highly prevalent among first-time visitors at a Norwegian dry eye specialist clinic 

      Badian, Reza; Utheim, Tor Paaske; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Ystenæs, Ann Elisabeth; Aakre, Bente Monica; Sundling, Vibeke (Peer reviewed; Journal article, 2021)
      To investigate the prevalence of meibomian gland dysfunction (MGD) in patients presenting with subjective dry eye-related symptoms at their first-time consultation in a Norwegian specialized ocular surface clinic. Additionally, ...

    • Meibomian Gland Morphology is a Sensitive Early Indicator of Meibomian Gland Dysfunction 

      Adil, Muhammed Yasin; Xiao, J; Olaffson, J.S.; Chen, Xiangjun; Lagali, Neil; Ræder, Sten; Utheim, Øygunn Aass; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)
      Purpose To investigate the relationship between meibomian gland (MG) morphology and clinical dry eye tests in patients with meibomian gland dysfunction (MGD). Design Cross-sectional study. Subjects Total 538 MGD patients ...

    • Seasonal variations in presenting symptoms and signs of dry eye disease in Norway 

      Eidet, Jon Roger; Chen, Xiangjun; Ræder, Sten; Badian, Reza; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)
      The study investigated the seasonal variations of presenting symptoms and signs of dry eye disease (DED) in Norway. 652 consecutive DED patients examined between August 2012 and May 2015 in Oslo, Norway, were included. ...

    • Tear production levels and dry eye disease severity in a large Norwegian cohort 

      Yazdani, Mazyar; Chen, Xiangjun; Tashbayev, Behzod; Utheim, Øygunn Aass; Ræder, Sten; Lagli, Neil; Stojanovic, Aleksandar; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)
      Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ...

    • TheraPearl Eye Mask and Blephasteam for the treatment of meibomian gland dysfunction: a randomized, comparative clinical trial 

      Olafsson, Jonatan; Lai, Xiaoran; Landsend, Erlend Christoffer Sommer; Olafsson, Snorri; Parissi, Eric; Utheim, Øygunn Aass; Ræder, Sten; Badian, Reza; Lagali, Neil Satish; Dartt, Darlene A.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2021)
      Meibomian gland dysfunction (MGD) is the most common cause of dry eye disease (DED). In this study, we aimed to compare the effects of eyelid warming treatment using either TheraPearl Eye Mask (Bausch & Lomb Inc., New York, ...

    • Transcriptome Analysis of Cultured Limbal Epithelial Cells on an Intact Amniotic Membrane following Hypothermic Storage in Optisol-GS 

      Utheim, Tor Paaske; Salvanos, Panagiotis; Utheim, Øygunn Aass; Ræder, Sten; Pasovic, Lara; Olstad, Ole Kristoffer; De la paz, Maria; Sehic, Amer (Journal article; Peer reviewed, 2016)
      The aim of the present study was to investigate the molecular mechanisms underlying activation of cell death pathways using genome-wide transcriptional analysis in human limbal epithelial cell (HLEC) cultures following ...

    • Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease 

      Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann; Chen, Xiangjun (Peer reviewed; Journal article, 2020)
      The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...