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dc.contributor.authorSand, Mari Kathrine
dc.contributor.authorCholidis, Symira
dc.contributor.authorRimstad, Kjartan
dc.contributor.authorKrekling, Elise Dees
dc.contributor.authorKristianslund, Olav
dc.contributor.authorDrolsum, Liv Kari
dc.date.accessioned2021-11-08T09:18:35Z
dc.date.available2021-11-08T09:18:35Z
dc.date.created2021-10-24T17:58:03Z
dc.date.issued2021
dc.identifier.citationSand, M. K., Cholidis, S., Rimstad, K., Krekling, E. D., Kristianslund, O., & Drolsum, L. (2021). Long-term outcome of primary intraocular lens implantation in bilateral congenital cataract in infants with a median age of 35 days at surgery: a case series. BMJ Open Ophthalmology, 6, Artikkel e000836.en_US
dc.identifier.issn2397-3269
dc.identifier.urihttps://hdl.handle.net/11250/2828287
dc.description.abstractObjective: To evaluate the long-term visual outcome and safety after bilateral cataract surgery with primary intraocular lens (IOL) implantation in infants with visually significant cataract at birth operated before 12 weeks of age. Methods and analysis: Medical records of infants with congenital cataract who had bilateral surgery with primary IOL implantation before 12 weeks of age at Oslo University Hospital between 2007 and 2016 were retrospectively reviewed. Fifteen infants (30 eyes) were enrolled for a prospective study examination in 2017. Corrected distance visual acuity (CDVA) and intraocular pressure (IOP) were assessed. Visual axis opacification (VAO) was defined as opacification on the anterior or posterior surface of the IOL, capsular phimosis or fibrinous membrane. Secondary glaucoma was evaluated according to international guidelines. Results: Median age at the time of primary surgery was 35 days (range, 15 to 70 days). There were no serious intraoperative complications, and all eyes had the IOL implanted in the capsular bag. After a median follow-up of 6.1 years (range, 1.5 to 10.2 years), the CDVA was 0.5 logMAR (range, 1.2 to 0.04). All eyes had surgery for VAO and the median number of surgical procedures was 2.0 (range, 1 to 5). The cumulative incidence of secondary glaucoma was 10% after 5 years of follow-up. Conclusion: Primary IOL implantation before 12 weeks of age gave a satisfactory visual outcome, and the incidence of secondary glaucoma was similar to that reported after primary IOL implantation in older infants. However, the risk of VAO was high.en_US
dc.language.isoengen_US
dc.rightsNavngivelse-Ikkekommersiell 4.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/deed.no*
dc.titleLong-term outcome of primary intraocular lens implantation in bilateral congenital cataract in infants with a median age of 35 days at surgery: A case seriesen_US
dc.typePeer revieweden_US
dc.typeJournal articleen_US
dc.description.versionpublishedVersionen_US
dc.rights.holder© Author(s) (or their employer(s)) 2021.en_US
dc.source.volume6en_US
dc.source.journalBMJ Open Ophthalmologyen_US
dc.identifier.doihttps://doi.org/10.1136/bmjophth-2021-000836
dc.identifier.cristin1948041
dc.source.articlenumbere000836en_US
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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Navngivelse-Ikkekommersiell 4.0 Internasjonal
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