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dc.contributor.authorZhao, Xinyan
dc.contributor.authorDong, Tao
dc.date.accessioned2017-12-21T11:55:50Z
dc.date.available2017-12-21T11:55:50Z
dc.date.created2014-01-10T14:25:36Z
dc.date.issued2013
dc.identifier.citationInternational Journal of Environmental Research and Public Health. 2013, 10 (12), 6748-6763.nb_NO
dc.identifier.issn1660-4601
dc.identifier.urihttp://hdl.handle.net/11250/2473501
dc.description.abstractA bioluminescent-cell-based microfluidic device for sensing toxicants in drinking water was designed and fabricated. The system employed Vibrio fischeri cells as broad-spectrum sensors to monitor potential systemic cell toxicants in water, such as heavy metal ions and phenol. Specifically, the chip was designed for continuous detection. The chip design included two counter-flow micromixers, a T-junction droplet generator and six spiral microchannels. The cell suspension and water sample were introduced into the micromixers and dispersed into droplets in the air flow. This guaranteed sufficient oxygen supply for the cell sensors. Copper (Cu2+), zinc (Zn2+), potassium dichromate and 3,5-dichlorophenol were selected as typical toxicants to validate the sensing system. Preliminary tests verified that the system was an effective screening tool for acute toxicants although it could not recognize or quantify specific toxicants. A distinct non-linear relationship was observed between the zinc ion concentration and the Relative Luminescence Units (RLU) obtained during testing. Thus, the concentration of simple toxic chemicals in water can be roughly estimated by this system. The proposed device shows great promise for an early warning system for water safety.nb_NO
dc.language.isoengnb_NO
dc.relation.urihttp://www.mdpi.com/1660-4601/10/12/6748
dc.rightsNavngivelse 3.0 Internasjonal*
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/deed.no*
dc.titleA microfluidic device for continuous sensing of systemic acute toxicants in drinking waternb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.source.pagenumber6748-6763nb_NO
dc.source.volume10nb_NO
dc.source.journalInternational Journal of Environmental Research and Public Healthnb_NO
dc.source.issue12nb_NO
dc.identifier.doi10.3390/ijerph10126748
dc.identifier.cristin1087667
dc.relation.projectNorges forskningsråd: 197411nb_NO
dc.relation.projectNorges forskningsråd: 190086nb_NO
dc.relation.projectAndre: Oslofjorfondet 229857nb_NO
dc.relation.projectAndre: Oslofjorfondet 220635nb_NO
cristin.unitcode222,58,4,0
cristin.unitnameInstitutt for mikrosystemer
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


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