Show simple item record

dc.contributor.authorPires, Nuno Miguel Matos
dc.contributor.authorDong, Tao
dc.contributor.authorHanke, Ulrik
dc.contributor.authorHoivik, Nils
dc.date.accessioned2017-12-12T14:37:50Z
dc.date.available2017-12-12T14:37:50Z
dc.date.created2015-02-02T15:13:38Z
dc.date.issued2014
dc.identifier.citationSensors. 2014, 14 (8), 15458-15479.nb_NO
dc.identifier.issn1424-8220
dc.identifier.urihttp://hdl.handle.net/11250/2470873
dc.description.abstractThe field of microfluidics has yet to develop practical devices that provide real clinical value. One of the main reasons for this is the difficulty in realizing low-cost, sensitive, reproducible, and portable analyte detection microfluidic systems. Previous research has addressed two main approaches for the detection technologies in lab-on-a-chip devices: (a) study of the compatibility of conventional instrumentation with microfluidic structures, and (b) integration of innovative sensors contained within the microfluidic system. Despite the recent advances in electrochemical and mechanical based sensors, their drawbacks pose important challenges to their application in disposable microfluidic devices. Instead, optical detection remains an attractive solution for lab-on-a-chip devices, because of the ubiquity of the optical methods in the laboratory. Besides, robust and cost-effective devices for use in the field can be realized by integrating proper optical detection technologies on chips. This review examines the recent developments in detection technologies applied to microfluidic biosensors, especially addressing several optical methods, including fluorescence, chemiluminescence, absorbance and surface plasmon resonance.nb_NO
dc.language.isoengnb_NO
dc.titleRecent developments in optical detection technologies in Lab-on-a-Chip devices for biosensing applicationsnb_NO
dc.typeJournal articlenb_NO
dc.typePeer reviewednb_NO
dc.description.versionpublishedVersionnb_NO
dc.rights.holder© 2014 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).nb_NO
dc.source.pagenumber15458-15479nb_NO
dc.source.volume14nb_NO
dc.source.journalSensorsnb_NO
dc.source.issue8nb_NO
dc.identifier.doi10.3390/s140815458
dc.identifier.cristin1215617
dc.relation.projectAndre: Oslofjordfondet m.fl. 234972nb_NO
dc.relation.projectNorges forskningsråd: 241063nb_NO
dc.relation.projectAndre: Oslofjordfondet 229857nb_NO
cristin.unitcode222,58,4,0
cristin.unitnameInstitutt for mikrosystemer
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode1


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record