Browsing 7 Sykehuset Telemark by Subject "762"
Now showing items 1-16 of 16
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Association between cigarette smoking, APC mutations and the risk of developing sporadic colorectal adenomas and carcinomas
(Journal article; Peer reviewed, 2006-03-17)BACKGROUND: The association between colorectal cancer (CRC) and smoking has not been consistent. Incomplete smoking history and association to a specific subset of CRC tumors have been proposed as explanations. The adenomatous ... -
CRC screening: review of the evidence and suggestions on when and how to move on from randomized trials to screening programmes
(Journal article; Peer reviewed, 2004) -
Effects of polymorphisms in ERCC1, ASE-1 and RAI on the risk of colorectal carcinomas and adenomas: a case control study
(Journal article; Peer reviewed, 2006-07-03)BACKGROUND: The risk of sporadic colorectal cancer is mainly associated with lifestyle factors and may be modulated by several genetic factors of low penetrance. Genetic variants represented by single nucleotide polymorphisms ... -
Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma
(Journal article; Peer reviewed, 2007-10-12)BACKGROUND: It has recently been shown that NDRG2 mRNA is down-regulated or undetectable in several human cancers and cancer cell-lines. Although the function of NDRG2 is unknown, high NDRG2 expression correlates with ... -
GPX Pro198Leu and OGG1 Ser326Cys polymorphisms and risk of development of colorectal adenomas and colorectal cancer
(Journal article; Peer reviewed, 2005)Little is known about genetic risk factors for colorectal cancer. We assessed the association between polymorphisms in two genes involved in DNA repair of oxidative stress, GPX and OGG1, and risk of colorectal carcinoma ... -
Increased mRNA expression levels of ERCC1, OGG1 and RAI in colorectal adenomas and carcinomas
(Journal article; Peer reviewed, 2006-08-16)BACKGROUND: The majority of colorectal cancer (CRC) cases develop through the adenoma-carcinoma pathway. If an increase in DNA repair expression is detected in both early adenomas and carcinomas it may indicate that low ... -
Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas
(Journal article; Peer reviewed, 2007-12-19)BACKGROUND: The risk of sporadic colorectal cancer (CRC) is mainly associated with lifestyle factors, particularly dietary factors. Diets high in red meat and fat and low in fruit and vegetables are associated with an ... -
Med åpent blikk utenfor egen institusjon
(Journal article; Peer reviewed, 2001)Even in a country like Norway, with a poor reputation for investment in medical research, some studies may materialise against all odds. This is the story about the difficult start and first few years of flexible sigmoidoscopy ... -
Polymorphisms of the XRCC1, XRCC3 and XPD genes and risk of colorectal adenoma and carcinoma, in a Norwegian cohort: a case control study
(Journal article; Peer reviewed, 2006-03-16)BACKGROUND: Genetic polymorphisms in DNA repair genes may influence individual variation in DNA repair capacity, which may be associated with risk of developing cancer. For colorectal cancer the importance of mutations in ... -
Quality control in colorectal cancer screening: systematic microbiological investigation of endoscopes used in the NORCCAP (Norwegian Colorectal Cancer Prevention) trial
(Journal article; Peer reviewed, 2003-06-13)BACKGROUND: Endoscopic colorectal cancer (CRC) screening is currently implemented in many countries. Since endoscopes cannot be sterilised, the transmission of infectious agents through endoscopes has been a matter of ... -
Re: Baseline findings of the Italian multicenter randomized controlled trial of "once-only sigmoidoscopy"--SCORE
(Journal article; Peer reviewed, 2003) -
Screening for colorectal cancer
(Journal article; Peer reviewed, 2005)Colorectal cancer (CRC) is the most common cancer in the Nordic countries after breast and prostate cancer. About 15 000 new cancers are diagnosed and more than 7 000 patients will die from CRC in 2005. CRC fulfils most ... -
Testing for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT)
(Journal article; Peer reviewed, 2004)BACKGROUND: Screening for colorectal cancer (CRC) using guaiac based faecal occult blood tests (FOBT) has an estimated programme sensitivity of >60% but <30% for strictly asymptomatic CRC in a single screening round. In ... -
The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals
(Journal article; Peer reviewed, 2006-07-04)BACKGROUND: It has recently been shown that overexpression of the serine protease, matriptase, in transgenic mice causes a dramatically increased frequency of carcinoma formation. Overexpression of HAI-1 and matriptase ... -
The science and politics of colorectal cancer screening
(Journal article; Peer reviewed, 2006) -
Use of a disposable sheath system for flexible sigmoidoscopy in decentralized colorectal cancer screening
(Journal article; Peer reviewed, 2002)Background and Study Aims: To prevent transmission of infectious agents and to reduce instrument reprocessing time, the use of disposable sheath systems instead of conventionally reprocessed endoscopes has been promoted ...