Blar i Institutt for natur, helse og miljø på forfatter "Lingjærde, Ole Christian"
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Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer
Hamfjord, Julian; Guren, Tormod Kyrre; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per; Dajani, Olav; Lingjærde, Ole Christian; Tveit, Magne Kjell; Pallisgaard, Niels; Spindler, Karen-Lise Garm; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2021)Detection of tumour-specific circulating cell-free DNA in plasma (ctDNA) fails in a significant number of cases depending on the clinical context. The primary aim was to investigate clinicopathological factors associated ... -
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Silwat-Pandit, Laxmi; Stålberg, Stina M.; Johansson, Henrik J.; Mermelekas, Georgios; Lothe, Inger Marie Bowitz; Skrede, Martina Landschoof; Dalsgaard, Astrid Marie; Nebdal, Daniel J. H.; Helland, Åslaug; Lingjærde, Ole Christian; Labori, Knut Jørgen; Skålhegg, Bjørn Steen; Lehtiö, Janne; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2022)Pancreatic cancer remains a disease with unmet clinical needs and inadequate diagnostic, prognostic, and predictive biomarkers. In-depth characterization of the disease proteome is limited. This study thus aims to define ... -
Total circulating cell-free DNA as a prognostic biomarker in metastatic colorectal cancer before first-line oxaliplatin-based chemotherapy
Hamfjord, Julian; Guren, Tormod Kyrre; Dajani, Olav; Johansen, Julia Sidenius; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per; Lingjærde, Ole Christian; Tveit, Magne Kjell; Kure, Elin H.; Pallisgaard, Niels; Spindler, Karen-Lise Garm (Journal article; Peer reviewed, 2019)Background Metastatic colorectal cancer (mCRC) is a heterogeneous disease where prognosis is dependent both on tumor biology and host factors. Total circulating cell-free DNA (cfDNA) has shown to harbor prognostic ...