Browsing USN Open Archive by Author "Vogel, Lotte K."

Now showing items 1-3 of 3

    • Expression of NDRG2 is down-regulated in high-risk adenomas and colorectal carcinoma 

      Lorentzen, Anders; Vogel, Lotte K.; Lewinsky, Rikke H.; Sæbø, Mona; Skjelbred, Camilla Furu; Godiksen, Sine; Hoff, Geir; Lothe, Inger Marie Bowitz; Ikdahl, Tone; Kure, Elin H.; Mitchelmore, Cathy (Journal article; Peer reviewed, 2007-10-12)
      BACKGROUND: It has recently been shown that NDRG2 mRNA is down-regulated or undetectable in several human cancers and cancer cell-lines. Although the function of NDRG2 is unknown, high NDRG2 expression correlates with ...

    • The level of claudin-7 is reduced as an early event in colorectal carcinogenesis 

      Bornholdt, Jette; Friis, Stine; Godiksen, Sine; Poulsen, Steen S.; Santoni-Rugiu, Eric; Bisgaard, Hanne C.; Lothe, Inger Marie Bowitz; Andersen, Tone Ikdahl; Tveit, Magne Kjell; Johnson, Egil; Kure, Elin H.; Vogel, Lotte K. (Journal article; Peer reviewed, 2011-02-10)
      BACKGROUND: Compromised epithelial barriers are found in dysplastic tissue of the gastrointestinal tract. Claudins are transmembrane proteins important for tight junctions. Claudins regulate the paracellular transport and ...

    • The ratio of Matriptase/HAI-1 mRNA is higher in colorectal cancer adenomas and carcinomas than corresponding tissue from control individuals 

      Vogel, Lotte K.; Sæbø, Mona; Skjelbred, Camilla Furu; Abell, Kathrine; Pedersen, Esben D.K.; Vogel, Ulla; Kure, Elin H. (Journal article; Peer reviewed, 2006-07-04)
      BACKGROUND: It has recently been shown that overexpression of the serine protease, matriptase, in transgenic mice causes a dramatically increased frequency of carcinoma formation. Overexpression of HAI-1 and matriptase ...