Browsing USN Open Archive by Author "Labori, Knut Jørgen"
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Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer
Braadland, Peder Rustøen; Farnes, Ingvild; Kure, Elin Wenche Hegland; Yaqub, Sheraz; McCann, Adrian; Ueland, Per Magne; Labori, Knut Jørgen; Hov, Johannes Espolin Roksund (Peer reviewed; Journal article, 2024)Background/Aims: It was recently reported that a higher concentration of the bacterially produced metabolite indole 3-acetate (3-IAA) in blood was linked to a better response to chemotherapy in patients with metastatic ... -
Meta-Analysis of 1,200 Transcriptomic Profiles Identifies a Prognostic Model for Pancreatic Ductal Adenocarcinoma
Sandhu, Vandana; Labori, Knut Jørgen; Borgida, Ayelet; Lungu, Ilinca; Bartlett, John; Hafezi-Bakhtiari, Sara; Denroche, Robert E.; Jang, Gun Ho; Pasternack, Danielle; Mbaabali, Faridah; Watson, Matthew; Wilson, Julie; Kure, Elin H.; Gallinger, Steven; Haibe-Kains, Benjamin (Peer reviewed; Journal article, 2019)PURPOSE: With a dismal 8% median 5-year overall survival, pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy. Only 10% to 20% of patients are eligible for surgery, and more than 50% of these patients ... -
Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome
Silwat-Pandit, Laxmi; Stålberg, Stina M.; Johansson, Henrik J.; Mermelekas, Georgios; Lothe, Inger Marie Bowitz; Skrede, Martina Landschoof; Dalsgaard, Astrid Marie; Nebdal, Daniel J. H.; Helland, Åslaug; Lingjærde, Ole Christian; Labori, Knut Jørgen; Skålhegg, Bjørn Steen; Lehtiö, Janne; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2022)Pancreatic cancer remains a disease with unmet clinical needs and inadequate diagnostic, prognostic, and predictive biomarkers. In-depth characterization of the disease proteome is limited. This study thus aims to define ...