Browsing USN Open Archive by Author "Kure, Elin Wenche Hegland"

Now showing items 1-5 of 5

    • Clinicopathological factors associated with tumour-specific mutation detection in plasma of patients with RAS-mutated or BRAF-mutated metastatic colorectal cancer 

      Hamfjord, Julian; Guren, Tormod Kyrre; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per; Dajani, Olav; Lingjærde, Ole Christian; Tveit, Magne Kjell; Pallisgaard, Niels; Spindler, Karen-Lise Garm; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2021)
      Detection of tumour-specific circulating cell-free DNA in plasma (ctDNA) fails in a significant number of cases depending on the clinical context. The primary aim was to investigate clinicopathological factors associated ...

    • Exploring Early Kinetic Profiles of CEA, ctDNA and cfDNA in Patients With RAS-/BRAF-Mutated Metastatic Colorectal Cancer 

      Hamfjord, Julian; Guren, Tormod Kyrre; Glimelius, Bengt; Sorbye, Halfdan; Pfeiffer, Per; Dajani, Olav; Lingjærde, Ole Christian; Tveit, Magne Kjell; Spindler, Karen-Lise Garm; Pallisgaard, Niels; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2024)
      Introduction: Patients with metastatic colorectal cancer (mCRC) respond differently to first-line chemotherapy. Early identification of patients with limited or no clinical benefit could prompt a timelier introduction of ...

    • Indole 3-acetate and response to therapy in borderline resectable or locally advanced pancreatic cancer 

      Braadland, Peder Rustøen; Farnes, Ingvild; Kure, Elin Wenche Hegland; Yaqub, Sheraz; McCann, Adrian; Ueland, Per Magne; Labori, Knut Jørgen; Hov, Johannes Espolin Roksund (Peer reviewed; Journal article, 2024)
      Background/Aims: It was recently reported that a higher concentration of the bacterially produced metabolite indole 3-acetate (3-IAA) in blood was linked to a better response to chemotherapy in patients with metastatic ...

    • Preoperative profiles of plasma amino acids and derivatives distinguish periampullary cancer and benign disease 

      Stålberg, Stina Margrethe; Silwal-Pandit, Laxmi; Bastani, Nasser Ezzatkhah; Nebdal, Daniel J.H.; Lingjærde, Ole Christian; Skålhegg, Bjørn Steen; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2024)
      Periampullary cancers, including pancreatic ductal adenocarcinoma, ampullary-, cholangio-, and duodenal carcinoma, are frequently diagnosed in an advanced stage and are associated with poor overall survival. They are ...

    • Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome 

      Silwat-Pandit, Laxmi; Stålberg, Stina M.; Johansson, Henrik J.; Mermelekas, Georgios; Lothe, Inger Marie Bowitz; Skrede, Martina Landschoof; Dalsgaard, Astrid Marie; Nebdal, Daniel J. H.; Helland, Åslaug; Lingjærde, Ole Christian; Labori, Knut Jørgen; Skålhegg, Bjørn Steen; Lehtiö, Janne; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2022)
      Pancreatic cancer remains a disease with unmet clinical needs and inadequate diagnostic, prognostic, and predictive biomarkers. In-depth characterization of the disease proteome is limited. This study thus aims to define ...