Browsing USN Open Archive by Author "Helland, Åslaug"

Now showing items 1-4 of 4

    • Molecular characterisation of TP53 mutated squamous cell carcinomas of the lung to identify putative targets for therapy 

      Haakensen, Vilde Drageset; Khadse, Anand; Sandhu, Vandana; Halvorsen, Ann Rita; Solberg, Steinar; Jørgensen, Lars Hilmar; Brustugun, Odd Terje; Kure, Elin H.; Helland, Åslaug (Peer reviewed; Journal article, 2020)
      Personalised cancer treatment depends on identification of therapeutically relevant biological subgroups of patients for assessing effect of treatment and to discover new therapeutic options. By analyses in heterogeneous ...

    • Non-small cell lung cancer is characterised by a distinct inflammatory signature in serum compared with chronic obstructive pulmonary disease 

      Eide, Hanne Astrid; Halvorsen, Ann Rita; Sandhu, Vandana; Fåne, Anne; Berg, Janna; Haakensen, Vilde Drageset; Kure, Elin H.; Brustugun, Odd Terje; Kiserud, Cecilie E.; Kyte, Jon A; Helland, Åslaug (Journal article; Peer reviewed, 2016)
      Development of lung cancer is closely related to smoking in a majority of patients. Most smokers, however, do not develop lung cancer in spite of a high mutational load accumulating in the lung tissue. Here we investigate ...

    • Proteome Analysis of Pancreatic Tumors Implicates Extracellular Matrix in Patient Outcome 

      Silwat-Pandit, Laxmi; Stålberg, Stina M.; Johansson, Henrik J.; Mermelekas, Georgios; Lothe, Inger Marie Bowitz; Skrede, Martina Landschoof; Dalsgaard, Astrid Marie; Nebdal, Daniel J. H.; Helland, Åslaug; Lingjærde, Ole Christian; Labori, Knut Jørgen; Skålhegg, Bjørn Steen; Lehtiö, Janne; Kure, Elin Wenche Hegland (Peer reviewed; Journal article, 2022)
      Pancreatic cancer remains a disease with unmet clinical needs and inadequate diagnostic, prognostic, and predictive biomarkers. In-depth characterization of the disease proteome is limited. This study thus aims to define ...

    • Serum cytokine profiles and metabolic tumor burden in patients with non-small cell lung cancer undergoing palliative thoracic radiation therapy 

      Eide, Hanne Astrid; Knudtsen, Ingerid Skjei; Sandhu, Vandana; Løndalen, Ayca; Halvorsen, Ann Rita; Abravan, Azadeh; Kure, Elin H.; Bogsrud, Trond; Brustugun, Odd Terje; Kyte, Jon A; Malinen, Eirik; Helland, Åslaug (Journal article; Peer reviewed, 2018)
      Purpose: Radiation therapy effectively kills cancer cells and elicits local effects in the irradiated tissue. The aim of this study was to investigate the kinetics of cytokines in the serum of patients with lung cancer ...