• Diagnostic Test Efficacy of Meibomian Gland Morphology and Function 

      Xiao, Jiaxin; Adil, Muhammed Yasin; Olafsson, Jonatan; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Lagali, Neil; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2019)
      Meibomian gland dysfunction (MGD) is the leading cause of dry eye and proposed treatments are based on disease severity. Our purpose was to establish reliable morphologic measurements of meibomian glands for evaluating MGD ...
    • Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia 

      Landsend, Erlend Christoffer Sommer; Pedersen, Hilde Røgeberg; Utheim, Øygunn Aass; Xiao, Jiaxin; Adil, Muhammed Yasin; Tashbayev, Behzod; Lagali, Neil; Dartt, Darlene Ann; Baraas, Rigmor C.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)
      Aims To investigate the aetiology and characteristics of dry eye disease (DED) in a Nordic cohort of patients with congenital aniridia. Methods Thirty-four Norwegian and one Danish subject with congenital aniridia and 21 ...
    • Tear production levels and dry eye disease severity in a large Norwegian cohort 

      Yazdani, Mazyar; Chen, Xiangjun; Tashbayev, Behzod; Utheim, Øygunn Aass; Ræder, Sten; Lagli, Neil; Stojanovic, Aleksandar; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)
      Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ...
    • The level of inflammatory tear cytokines is elevated in congenital Aniridia and associated with meibomian gland dysfunction 

      Landsend, Erlend Christoffer Sommer; Utheim, Øygunn Aass; Pedersen, Hilde Røgeberg; Aass, Hans Christian Dalsbotten; Lagali, Neil; Dartt, Darlene Ann; Baraas, Rigmor C.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)
      Purpose: To investigate the tear cytokine profile in congenital aniridia, and correlate cytokine levels with ophthalmologic findings. Methods: We examined 35 patients with aniridia and 21 healthy controls. Tear fluid ...
    • Tissue harvesting site and culture medium affect attachment, growth, and phenotype of ex vivo expanded oral mucosal epithelial cells 

      Islam, Rakibul; Eidet, Jon Roger; Badian, Reza; Lippestad, Marit; Messelt, Edvard Berger; Griffith, May; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2017)
      Transplantation of cultured oral mucosal epithelial cells (OMECs) is a promising treatment strategy for limbal stem cell deficiency. In order to improve the culture method, we investigated the effects of four culture media ...