Browsing USN Open Archive by Author "Dartt, Darlene Ann"
Now showing items 1-7 of 7
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Diagnostic Test Efficacy of Meibomian Gland Morphology and Function
Xiao, Jiaxin; Adil, Muhammed Yasin; Olafsson, Jonatan; Chen, Xiangjun; Utheim, Øygunn Aass; Ræder, Sten; Lagali, Neil; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2019)Meibomian gland dysfunction (MGD) is the leading cause of dry eye and proposed treatments are based on disease severity. Our purpose was to establish reliable morphologic measurements of meibomian glands for evaluating MGD ... -
Hot towels: The bedrock of Meibomian gland dysfunction treatment – A review
Magnø, Morten Schjerven; Olafsson, Jonatan; Beining, Marie Wangen; Moschowits, Emily; Lagali, Neil Satish; Wolffsohn, James S.; Craig, Jennifer P.; Vehof, Jelle; Dartt, Darlene Ann; Utheim, Tor Paaske (Peer reviewed; Journal article, 2022)Background: Meibomian gland dysfunction (MGD) reduces quality-of-life and hinders work productivity of millions of patients, with high direct and indirect societal costs. Thickened meibum obstructs the glands and disrupts ... -
Meibomian gland dysfunction and keratopathy are associated with dry eye disease in aniridia
Landsend, Erlend Christoffer Sommer; Pedersen, Hilde Røgeberg; Utheim, Øygunn Aass; Xiao, Jiaxin; Adil, Muhammed Yasin; Tashbayev, Behzod; Lagali, Neil; Dartt, Darlene Ann; Baraas, Rigmor C.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)Aims To investigate the aetiology and characteristics of dry eye disease (DED) in a Nordic cohort of patients with congenital aniridia. Methods Thirty-four Norwegian and one Danish subject with congenital aniridia and 21 ... -
Tear production levels and dry eye disease severity in a large Norwegian cohort
Yazdani, Mazyar; Chen, Xiangjun; Tashbayev, Behzod; Utheim, Øygunn Aass; Ræder, Sten; Lagli, Neil; Stojanovic, Aleksandar; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)Purpose: To determine if the Schirmer I test (without anesthesia) cut-off value is a predictor of dry eye severity in a large Norwegian cohort of dry eye disease (DED) patients, which are grouped into six levels of tear ... -
The level of inflammatory tear cytokines is elevated in congenital Aniridia and associated with meibomian gland dysfunction
Landsend, Erlend Christoffer Sommer; Utheim, Øygunn Aass; Pedersen, Hilde Røgeberg; Aass, Hans Christian Dalsbotten; Lagali, Neil; Dartt, Darlene Ann; Baraas, Rigmor C.; Utheim, Tor Paaske (Journal article; Peer reviewed, 2018)Purpose: To investigate the tear cytokine profile in congenital aniridia, and correlate cytokine levels with ophthalmologic findings. Methods: We examined 35 patients with aniridia and 21 healthy controls. Tear fluid ... -
Tissue harvesting site and culture medium affect attachment, growth, and phenotype of ex vivo expanded oral mucosal epithelial cells
Islam, Rakibul; Eidet, Jon Roger; Badian, Reza; Lippestad, Marit; Messelt, Edvard Berger; Griffith, May; Dartt, Darlene Ann; Utheim, Tor Paaske (Journal article; Peer reviewed, 2017)Transplantation of cultured oral mucosal epithelial cells (OMECs) is a promising treatment strategy for limbal stem cell deficiency. In order to improve the culture method, we investigated the effects of four culture media ... -
Utility of Tear Osmolarity Measurement in Diagnosis of Dry Eye Disease
Tashbayev, Behzod; Utheim, Tor Paaske; Utheim, Øygunn Aass; Ræder, Sten; Jensen, Janicke Cecilie Liaaen; Yazdani, Mazyar; Lagali, Neil Satish; Vitelli, Valeria; Dartt, Darlene Ann; Chen, Xiangjun (Peer reviewed; Journal article, 2020)The prevalence of dry eye disease is high worldwide and poses a great burden on patients’ daily lives. Accurate diagnosis of the disease is important, and it requires application of various methods. Hyperosmolarity is ...