Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity—A Randomized Controlled Trial
Berge, Jarle; Hjelmesæth, Jøran; Hertel, Jens Kristoffer; Gjevestad, Espen Svendsen; Småstuen, Milada Cvancarova; Johnson, Line Kristin; Martins, Catia; Andersen, Eivind; Helgerud, Jan; Støren, Øyvind
Journal article, Peer reviewed
Published version
![Thumbnail](/usn-xmlui/bitstream/handle/11250/2738865/Berge%2b2121%2boby.23078.pdf.jpg?sequence=6&isAllowed=y)
View/ Open
Date
2021Metadata
Show full item recordCollections
Original version
Berge, J., Hjelmesæth, J., Hertel, J. K., Gjevestad, E., Småstuen, M. C., Johnson, L. K., ... & Støren, Ø. (2021). Effect of Aerobic Exercise Intensity on Energy Expenditure and Weight Loss in Severe Obesity—A Randomized Controlled Trial. Obesity, 29(2), 359-369. https://doi.org/10.1002/oby.23078Abstract
Objective: This study aimed to compare the effects of two aerobic exercise programs of different intensities on energy expenditure.
Methods: This was a single‐center randomized controlled trial of patients with severe obesity allocated to a 24‐week moderate‐intensity continuous training (MICT) program or a combined MICT with high‐intensity interval training (HIIT/MICT) program. The primary outcome was energy expenditure during exercise (EEDE). Secondary outcomes included resting metabolic rate, cardiorespiratory fitness, and body composition.
Results: A total of 82 (56% females) patients were screened, and 71 (55% females) patients were allocated to HIIT/MICT (n = 37) or MICT (n = 34). Per‐protocol analysis showed that EEDE increased by 10% (95% CI: 3%‐17%) in the HIIT/MICT group (n = 16) and 7.5% (95% CI: 4%‐10%) in the MICT group (n = 24), with no differences between groups. In the 8‐ to 16‐ week per‐protocol analysis, the HIIT/MICT group had a significantly larger increase in EEDE compared with the MICT group. Resting metabolic rate remained unchanged in both groups. HIIT/MICT and MICT were associated with significant weight loss of 5 kg and 2 kg, respectively.
Conclusions: Patients completing a 24‐week combined HIIT/MICT program did not achieve a higher EEDE compared with those who completed a 24‐week MICT program. The HIIT/MICT group experienced, on average, a 3‐kg‐larger weight loss than the MICT group.